provigal | Provigal | Provigil Medication Details

Provigal | Provigil Medication Details

Details of Provigil medication:

Provigil is manufactured by Cephalon Inc.  Also often known as Provigal, it has become very popular as a drug to remove sleepiness and keeping awake.  The actual drug is known as modafinil.

Mechanism of Action: Provigal is a cerebral stimulant.  However modafinil is structurally different from other cerebral stimulants.  The mechanism of action is not known, but it appears to differ from the usual stimulation of catecholamine or dopamine systems. Provigal does not appear to give rise to the withdrawal symptoms common in persons on long term cerebral stimulants. It is taken orally and is used to promote wakefulness in patients who have problems with excessive sleepiness.  This problem is seen in patients with Sleep Apnea, Narcolepsy and Shift Work Sleep Disorder, for which 3 problems the FDA has approved for usage.

Provigal is a prescription drug and comes in strengths of 100mg and 200mg modafinil.  Generic modafinil is not available at the present moment.

Provigil side effects are not common.  They are mostly nausea, headache and dry mouth.  Usage of provigal in pregnancy is not recommended as no studies have been or ever will be done in pregnant or nursing women, due to ethical issues.

What is interesting in Provigal is the off-label uses of the drug (off-label uses are uses not recommended or approved by the FDA, but recommended by doctors based on observation of clinical judgement of its effects).  Thus we see a lot of people taking Provigal to keep awake, and to improving their learning abilities.  Students use a lot of it to keep awake when cramming last minute for exams.  Wall Street and Silicon Valley executives use it to keep awake and maximise their waking hours.  Soldiers and helicopter pilots use it to keep awake when going on long missions.

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